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Analytical And Clinical Pharmacology

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Contact Person

  • Assoc. Prof Dr. Zamri Chik (zamrichik@ummc.edu.my)
  • Prof. Datin Dr. Zahurin Mohamed (zahurin@ummc.edu.my)
  • Dr. Roma Chowdury Basu (romacb@um.edu.my)
  • Mr. Didi Erwandi Mohamed Haron (didi27@um.edu.my)
  • Ms Noreena Nordin (noreen_crypt@yahoo.com)
Introduction

The Analytical and Toxicology group conducts research and services in various fields such as clinical study of medicine, food monitoring, environmental monitoring, pharmaceutical analysis, herbal and traditional medicines, and various biomedical and industrial related analyses. The research and services can be divided into two main fields which are analytical division and clinical division. Analytical division which involves the application of chromatographic techniques such as HPLC, GC/MS, LC/MS or LC/MS/MS are conducted in SUCXeS (Shimadzu UMMC Centre for Xenobiotic Studies) laboratory and the clinical research and services are mainly conducted in UBAT (University of Malaya Bioequivalence and Testing Centre). Clinical studies including the rest of other clinical trial phases are carried out in a Clinical Study Ward, University Malaya Medical Centre (UMMC) by a Bioequivalence Study Group. The laboratory is accredited with MS ISO/IEC 17025 for chemical testing laboratory and clinical research centre (UBAT) is listed under the National Pharmaceutical Regulatory Agency (NPRA) Malaysia GLP compliance to conduct bioequivalence study. With all the capacities and expertise in clinical and analytical area, this group is capable of conducting high quality research and services for:

  • Grant-funded research studies; Post graduate projects
  • Government bodies
  • Pharmaceutical companies
  • Contract Research Organisations (CRO)
  • Multicentre clinical trials
  • Research and Development Laboratories

 

Main Function

  1. Provides an opportunity to do research for graduate students and researchers in areas requiring analysis of drugs, pharmacokinetic studies, clinical trials, drug delivery studies such as topical and transdermal drug delivery system as well as for systemic delivery using palm oil base and nanoformulations.
  2. Provides consultation in analytical services and instrumentation for pharmaceutical industries and related government industry.
  3. Provides training facilities for laboratory staffs, students and workers in the industry in the use of analytical equipments such as HPLC, GC/MS, LC/MS etc. To date, we have successfully trained many students either at the undergraduate, masters, doctoral, and post doctoral level and conducted several certificate courses to government officers from different ministries and people from the private sector. Some of the courses offered include the practical use of the HPLC and the GC/MS which are rarely provided in Malaysia.
  4. Provide consultations/training for bioavailability/bioequivalence and pharmacokinetic studies in clinical phase as well as pre clinical phase

 

List of Equipments

  1. Shimadzu High Performance Liquid Chromatography with UV Detector (HPLC-UV)
  2. Shimadzu Ultra Fast Liquid Chromatography with UV Detector (UFLC-UV)
  3. Shimadzu Liquid Chromatography with MS (LCMS 2020)
  4. Shimadzu Liquid Chromatography with MS/MS (LC-MS/MS 8030) (1)
  5. Shimadzu Liquid Chromatography with MS/MS (LC-MS/MS 8030) (2)
  6. Liquid chromatography Tandem Mass Spectrometer AB Sciex Q Trap 5500 (LC-MS/MS)
  7. Liquid chromatography Tandem Mass Spectrometer AB Sciex API 3200 (LC-MS/MS)
  8. Shimadzu Gas Chromatography Mass Spectrometry (GCMS 2010)
  9. Shimadzu Gas Chromatography Mass Spectrometry (GCMS 5050A)
  10. Shimadzu UFLC (IT-TOF)

 

Clinical Study Ward

 

LCMSMS ABI SCIEX API3200 Equipment

Last Updated: 19/11/2018